Physiology of the gastro-intestinal tract, structure and functions of the kidney; physiology of endocrine glands, human reproduction. 

Body fluid compartments, blood, formation, functions, haemostasis, haemorrhage. Electrophysiology of the heart, cardiac cycle, venous return, circulatory adjustment to exercise, physiology of respiration. 

Introduction to plant products of primary metabolism. Photosynthesis and its significance to the production of natural products. Saccharides. Commercial starches. Pharmaceutical gums, resins, balsams, mucilages, natural sources and processing, identification and uses. 

Milling and size reduction. Mixing of solids and liquids. Separation of solids from liquids. Clarification and Filtration. Mass and heat transfer, drying principles and methods. Evaporation and distillation. 

i) Fundamental concepts and techniques of Organic Chemistry, bonding and reactivity of inorganic compounds, Hyperconjugative, steric resonance and delocalization. 

ii) Functional Group Chemistry; 

A consideration of the Nomenclature, structure, preparation and properties, illustrated with relevant reactions and pharmaceutical examples of the major classes of organic compounds and introducing elements of medicinal chemistry. 

iii) Strength of acids and bases. 

iv) Organometallic compounds. 

(v) Introduction of stereo-chemistry of compounds; structural ostereoisomerism (optical and geometrical); Optical activity and polarimetry; ORD/CD, molecular models and projection formulae; molecular dysimmetry. Racemization and resolution methods. 

(vi) Practicals – To complement the theoretical principles provided above. 

Basic knowledge of the physical Non-electrolyte solutions. Colligative properties and solubility of pharmaceuticals, osmotic pressure and isotonic solutions: 

(i) Chemical and ionic equilibria-general concepts, acid base equilibria, buffer solutions and pharmaceutical applications: 

(ii) Electro-chemical methods of analysis of pharmaceuticals. Electrolyte solutions and electro-chemistry, Conductimetry, potentiometry- principles, instrumentation and applications in pharmaceutical analysis, amperometric and dead-stop titration, Polarography – principle and analytical applications 

This is a 2nd year professional course for Pharmacy students. It involves introduction to dosage forms, definition and presentation of single dosage forms, classification and characteristics, factors influencing dosage form design and detailed consideration of selected dosage forms. Solution and Solubility Factors and Solubility curves are also considered.

Welcome to Physical Pharmaceutical Chemistry II

This is a 200 Level course which provides a comprehensive knowledge of thermodynamics, deals with the principles, facts and recent trends in rate of drug degradation and decomposition, kinetics of enzyme reactions, radiopharmacy as well as an introduction to drug analysis.